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Which hormone stimulates appetite via stimulation of the NPY receptors and growth hormone release?

  1. Insulin

  2. Leptin

  3. Cholecystokinin

  4. Ghrelin

The correct answer is: Ghrelin

Ghrelin is known as the "hunger hormone" because it plays a crucial role in stimulating appetite and is involved in energy balance. When ghrelin is released, it acts primarily on the hypothalamus, where it stimulates neuropeptide Y (NPY) receptors. This stimulation increases appetite and food intake. Additionally, ghrelin promotes the release of growth hormone from the pituitary gland, further influencing metabolism and growth. This highlights the hormone's dual function in both stimulating hunger and enhancing growth hormone levels, making it an essential factor in body weight regulation and energy homeostasis. Understanding the roles of ghrelin can provide insights into how appetite is regulated and could lead to strategies for managing weight and metabolic disorders.